교수소개

김진기 부교수

약학과
연구분야 : 약제학

연락처 : 031-400-5808

■ 학력
서울대학교 약학대학 제약학과 (약학사, 1998년)
서울대학교 대학원 약학과 (약학석사, 2000년)
서울대학교 대학원 제약학과 (약학박사, 2005년)

■ 경력
- 한양대학교 약학대학 약학과, 조교수 (2011.9 - 현재)
- 미국 노스캐롤라이나대학교 약학대학, Postdoctoral Research Associate (2010.4 - 2011.8)
- 미국 미시시피대학교 약학대학, Postdoctoral Fellow (2007.8 - 2010.3)
- 동덕여자대학교 대학원 약학과, 강사 (2007.3 - 2007.8)
- 서울대학교 BK21 응용생명약학사업단, 선임연구원(2006.5 - 2007.8)
- 서울대학교 종합약학연구소, 박사후연구원 (2005.3 – 2006.4)

■ 주요연구분야
1. 나노수송체를 이용한 난용성약물의 가용화 및 신제형 개발
2. 진단치료용 나노입자 개발
3. 생체감응성 신물질의 합성 및 제형 개발
4. 바이오의약품용 약물수송체 개발

■ 주요논문 (2008년 이후)
1. Anthony J. Di Pasqua1, Hong Yuan, Younjee Chung, Jin-Ki Kim, James E. Huckle, Chenxi Li, Matthew Sadgrove, Thanh Huyen Tran, Michael Jay, Xiuling Lu, Neutron-activatable holmium-containing mesoporous silica nanoparticles as a potential radionuclide therapeutic agent for ovarian cancer. J. Nucl. Med. [Epub ahead of print] (2012.10.25).
2. Jin-Ki Kim, Hong Yuan, Jingxin Nie, Markos Leggas, Philip M. Potter, John Rinehart, Michael Jay, Xiuling Lu, High payload dual therapeutic-imaging nanocarriers for triggered tumor delivery. Small 8(18), 2895-2903 (2012.09.24). 
3. Anthony J. Di Pasqua, James E. Huckle, Jin-Ki Kim, Younjee Chung, Andrew Z. Wang, Michael Jay, Xiuling Lu, Preparation of neutron-activatable holmium nanoparticles for the treatment of ovarian cancer metastases. Small 8(7), 997-1000 (2012.04.10).
4. Eun Kyung Oh, Su-Eon Jin, Jin-Ki Kim, Jeong-Sook Park, Youmie Park, Chong-Kook Kim, Retained topical delivery of 5-aminolevulinic acid using cationic ultradeformable liposome for photodynamic therapy. Eur. J. Pharm. Sci. 44(1-2), 149-157 (2011.09.18).
5. Jin-Ki Kim, Jun-Pil Jee, Jeong-Sook Park, Hyung Tae Kim, Chong-Kook Kim, Reverse-phase liquid chromatography with electrospray ionization/mass spectrometry for the quantification of pseudoephedrine in human plasma and application to a bioequivalence study. Arzneimittelforschung 61(5), 276-281 (2011.05.30).
6. Vivek Kumar Garripelli, Jin-Ki Kim, Sejin Son, Won Jong Kim, Michael A. Repka, Seongbong Jo, Matrix metalloproteinase-sensitive thermogelling polymer for bioresponsive local drug delivery. Acta Biomater. 7(2), 1984-1992 (2011.05.07).
7. Dong Il Kang, Sukmook Lee, Jung Tae Lee, Byung Je Sung, Ji-Yong Yoon, Jin-Ki Kim, Junho Chung, Soo Jeong Lim, Preparation and in vitro evaluation of anti-VCAM-1-Fab-conjugated liposomes for the targeted delivery of the poorly water-soluble drug celecoxib. J. Microencapsul. 28(3), 220-227 (2011.03).
8. Seo-Ryung Kim, Jin-Ki Kim, Jeong-Sook Park, Chong-Kook Kim, Dry elixir formulations of dexibuprofen for controlled release and enhanced oral bioavailability. Int. J. Pharm. 404(1-2), 301-307 (2011.02.14).
9. Jin-Ki Kim, Melissa D. Howard, Thomas D. Dziubla, John J. Rinehart, Michael Jay, Xiuling Lu, Uniformity of drug payload and its effect on stability of solid lipid nanoparticles containing an ester prodrug. ACS Nano 5(1), 209-216 (2011.01.25).
10. Jin-Ki Kim, Vivek Kumar Garripelli, Ui-Hyeon Jeong, Jeong-Sook Park, Michael A. Repka, Seongbong Jo, Novel pH-sensitive polyacetal-based block copolymers for controlled drug delivery. Int. J. Pharm. 401(1-2), 79-86 (2010. 11.30).
11. Ye-Tae Kim, Baek-Ki Shin, Vivek K. Garripelli, Jin-Ki Kim, Enkhzaya Davaa, Seongbong Jo, Jeong-Sook Park, A thermosensitive vaginal gel formulation with HPCD for the pH-dependent release and solubilization of amphotericin B. Eur. J. Pharm. Sci. 41(2), 399-406 (2010.10.09).
12. Vivek K. Garripelli, Jin-Ki Kim, Ran Namgung, Won Jong Kim, Michael A. Repka, Seongbong Jo, A novel thermosensitive polymer with pH-dependent degradation for drug delivery. Acta Biomater. 6(2), 477-485 (2010.02.01).
13. Jin-Ki Kim, Jeong-Sook Park, Chong-Kook Kim, Development of a binary lipid nanoparticles formulation of itraconazole for parenteral administration and controlled release. Int. J. Pharm. 383(1-2), 209-215 (2010.01.04)
14. Ji-Young Kim, Jin-Ki Kim, Jeong-Sook Park, Youngro Byun, Chong-Kook Kim, The use of PEGylated liposomes to prolong circulation lifetimes of tissue plasminogen activator, Biomaterials 30(29), 5751-5756 (2009.10.01).
15. Seung-Hee Baek, Sung Jin Park, Su-Eon Jin, Jin-Ki Kim, Chong-Kook Kim, Jeong-Min Hwang, Subconjunctivally injected, liposome-encapsulated streptokinase enhances the absorption rate of subconjunctival hemorrhages in rabbits. Eur. J. Pharm. Biopharm. 72(3), 546-551 (2009.08.01). 
16. Jin-Ki Kim, Joel Anderson, Ho-Wook Jun, Michael A. Repka, Seongbong Jo, Self-assembling peptide amphiphile-based nanofiber gel for bioresponsive cisplatin delivery. Mol. Pharmaceutics 6(3), 978-985 (2009.05.01).
17. Jin-Ki Kim, Myung-Sun Kim, Jeong-Sook Park, Chong-Kook Kim, Thermo-reversible flurbiprofen liquid suppository with HP-β-CD as a solubility enhancer: improvement of rectal bioavailability. J. Incl. Phenom. Macrocycl. Chem. 64(3-4), 265-272 (2009.03.13).
18. Sung-Hoon Kim, Jin-Ki Kim, Soo-Jeong Lim, Jeong-Sook Park, Mi-Kyung Lee, Chong-Kook Kim, Folate-tethered emulsion for the target delivery of retinoids to cancer cells. Eur. J. Pharm. Biopharm. 68(3), 618-625 (2008.03.01).
19. Meong Cheol Shin, Jin-Ki Kim, Chong-Kook Kim, Bioequivalence evaluation of two brands of lisinopril tablets by in vitro comparative dissolution test and in vivo bioequivalence test. Arzneimittelforschung 58(1), 11-17 (2008.01.30).
20. Yoonho Choi, Jin-Ki Kim, Eunmi Ban, Jeong-Sook Park, Chong-Kook Kim, Determination of losartan in human plasma by liquid chromatography electrospray inonization mass spectrometry (LC-ESI-MS): application to bioequivalence study, J. Liq. Chromatogr. & Rel. Tech. 31 (17), 2643-2656 (2008.01.01).

■ 특허
최한곤, 용철순, 이강춘, 김대덕 이동훈, 김종국, 김진기, 박명관, 새로운 이부프로펜 함유 젤라틴 초미세 미립구, 특허 제 10-0694235 호 (2007. 3. 6)

■ Education
- Ph. D. College of Pharmacy, Seoul National University, Republic of Korea (2005), Advisor: Chong-Kook Kim, Ph.D.
- M. S. College of Pharmacy, Seoul National University, Republic of Korea (2000)
- B. S. College of Pharmacy, Seoul National University, Republic of Korea (1998)

■ Research Experience
- 2011-present: Assistant Professor, Colllege of Pharmacy, Hanyang University
- 2010-2011: Postdoctoral Research Associate, Center for Nanotechnology in Drug Delivery, University of North Carolina at Chapel Hill
- 2007-2010:Postdoctoral Fellow, Department of Pharmaceutics, School of Pharmacy, University of MississippiResearch 
- 2006-2007: Postdoctoral Fellow, Research Division for Applied Pharmaceutical Life Sciences (Brain Korea 21 Project), Seoul National University
- 2005-2006: Postdoctoral Fellow, Research Institute of Pharmaceutical Sciences, 
College of Pharmacy, Seoul National University

■ Research Interests
- Lipid-based nanoparticulate system
- Theranostic nanoparticles for anticancer therapy 
- Bioresponsive drug delivery system for targeted drug delivery
- Carriers for biopharmaceutical proteins, antibodies, genes and vaccines

■ Publications (from 2008)
1. Anthony J. Di Pasqua1, Hong Yuan, Younjee Chung, Jin-Ki Kim, James E. Huckle, Chenxi Li, Matthew Sadgrove, Thanh Huyen Tran, Michael Jay, Xiuling Lu, Neutron-activatable holmium-containing mesoporous silica nanoparticles as a potential radionuclide therapeutic agent for ovarian cancer. J. Nucl. Med. [Epub ahead of print] (2012.10.25).
2. Jin-Ki Kim, Hong Yuan, Jingxin Nie, Markos Leggas, Philip M. Potter, John Rinehart, Michael Jay, Xiuling Lu, High payload dual therapeutic-imaging nanocarriers for triggered tumor delivery. Small 8(18), 2895-2903 (2012.09.24). 
3. Anthony J. Di Pasqua, James E. Huckle, Jin-Ki Kim, Younjee Chung, Andrew Z. Wang, Michael Jay, Xiuling Lu, Preparation of neutron-activatable holmium nanoparticles for the treatment of ovarian cancer metastases. Small 8(7), 997-1000 (2012.04.10).
4. Eun Kyung Oh, Su-Eon Jin, Jin-Ki Kim, Jeong-Sook Park, Youmie Park, Chong-Kook Kim, Retained topical delivery of 5-aminolevulinic acid using cationic ultradeformable liposome for photodynamic therapy. Eur. J. Pharm. Sci. 44(1-2), 149-157 (2011.09.18).
5. Jin-Ki Kim, Jun-Pil Jee, Jeong-Sook Park, Hyung Tae Kim, Chong-Kook Kim, Reverse-phase liquid chromatography with electrospray ionization/mass spectrometry for the quantification of pseudoephedrine in human plasma and application to a bioequivalence study. Arzneimittelforschung 61(5), 276-281 (2011.05.30).
6. Vivek Kumar Garripelli, Jin-Ki Kim, Sejin Son, Won Jong Kim, Michael A. Repka, Seongbong Jo, Matrix metalloproteinase-sensitive thermogelling polymer for bioresponsive local drug delivery. Acta Biomater. 7(2), 1984-1992 (2011.05.07).
7. Dong Il Kang, Sukmook Lee, Jung Tae Lee, Byung Je Sung, Ji-Yong Yoon, Jin-Ki Kim, Junho Chung, Soo Jeong Lim, Preparation and in vitro evaluation of anti-VCAM-1-Fab-conjugated liposomes for the targeted delivery of the poorly water-soluble drug celecoxib. J. Microencapsul. 28(3), 220-227 (2011.03).
8. Seo-Ryung Kim, Jin-Ki Kim, Jeong-Sook Park, Chong-Kook Kim, Dry elixir formulations of dexibuprofen for controlled release and enhanced oral bioavailability. Int. J. Pharm. 404(1-2), 301-307 (2011.02.14).
9. Jin-Ki Kim, Melissa D. Howard, Thomas D. Dziubla, John J. Rinehart, Michael Jay, Xiuling Lu, Uniformity of drug payload and its effect on stability of solid lipid nanoparticles containing an ester prodrug. ACS Nano 5(1), 209-216 (2011.01.25).
10. Jin-Ki Kim, Vivek Kumar Garripelli, Ui-Hyeon Jeong, Jeong-Sook Park, Michael A. Repka, Seongbong Jo, Novel pH-sensitive polyacetal-based block copolymers for controlled drug delivery. Int. J. Pharm. 401(1-2), 79-86 (2010. 11.30).
11. Ye-Tae Kim, Baek-Ki Shin, Vivek K. Garripelli, Jin-Ki Kim, Enkhzaya Davaa, Seongbong Jo, Jeong-Sook Park, A thermosensitive vaginal gel formulation with HPCD for the pH-dependent release and solubilization of amphotericin B. Eur. J. Pharm. Sci. 41(2), 399-406 (2010.10.09).
12. Vivek K. Garripelli, Jin-Ki Kim, Ran Namgung, Won Jong Kim, Michael A. Repka, Seongbong Jo, A novel thermosensitive polymer with pH-dependent degradation for drug delivery. Acta Biomater. 6(2), 477-485 (2010.02.01).
13. Jin-Ki Kim, Jeong-Sook Park, Chong-Kook Kim, Development of a binary lipid nanoparticles formulation of itraconazole for parenteral administration and controlled release. Int. J. Pharm. 383(1-2), 209-215 (2010.01.04)
14. Ji-Young Kim, Jin-Ki Kim, Jeong-Sook Park, Youngro Byun, Chong-Kook Kim, The use of PEGylated liposomes to prolong circulation lifetimes of tissue plasminogen activator, Biomaterials 30(29), 5751-5756 (2009.10.01).
15. Seung-Hee Baek, Sung Jin Park, Su-Eon Jin, Jin-Ki Kim, Chong-Kook Kim, Jeong-Min Hwang, Subconjunctivally injected, liposome-encapsulated streptokinase enhances the absorption rate of subconjunctival hemorrhages in rabbits. Eur. J. Pharm. Biopharm. 72(3), 546-551 (2009.08.01). 
16. Jin-Ki Kim, Joel Anderson, Ho-Wook Jun, Michael A. Repka, Seongbong Jo, Self-assembling peptide amphiphile-based nanofiber gel for bioresponsive cisplatin delivery. Mol. Pharmaceutics 6(3), 978-985 (2009.05.01).
17. Jin-Ki Kim, Myung-Sun Kim, Jeong-Sook Park, Chong-Kook Kim, Thermo-reversible flurbiprofen liquid suppository with HP-β-CD as a solubility enhancer: improvement of rectal bioavailability. J. Incl. Phenom. Macrocycl. Chem. 64(3-4), 265-272 (2009.03.13).
18. Sung-Hoon Kim, Jin-Ki Kim, Soo-Jeong Lim, Jeong-Sook Park, Mi-Kyung Lee, Chong-Kook Kim, Folate-tethered emulsion for the target delivery of retinoids to cancer cells. Eur. J. Pharm. Biopharm. 68(3), 618-625 (2008.03.01).
19. Meong Cheol Shin, Jin-Ki Kim, Chong-Kook Kim, Bioequivalence evaluation of two brands of lisinopril tablets by in vitro comparative dissolution test and in vivo bioequivalence test. Arzneimittelforschung 58(1), 11-17 (2008.01.30).
20. Yoonho Choi, Jin-Ki Kim, Eunmi Ban, Jeong-Sook Park, Chong-Kook Kim, Determination of losartan in human plasma by liquid chromatography electrospray inonization mass spectrometry (LC-ESI-MS): application to bioequivalence study, J. Liq. Chromatogr. & Rel. Tech. 31 (17), 2643-2656 (2008.01.01).